A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis

Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies. This phase 2 study assessed the efficacy and safety of maralixibat, a selective, ileal, apical, sodium‐dependent, bile a...

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Detalles Bibliográficos
Autores principales: Mayo, Marlyn J., Pockros, Paul J., Jones, David, Bowlus, Christopher L., Levy, Cynthia, Patanwala, Imran, Bacon, Bruce, Luketic, Velimir, Vuppalanchi, Raj, Medendorp, Sharon, Dorenbaum, Alejandro, Kennedy, Ciara, Novak, Patricia, Gu, Joan, Apostol, George, Hirschfield, Gideon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396374/
https://www.ncbi.nlm.nih.gov/pubmed/30859149
http://dx.doi.org/10.1002/hep4.1305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396374/
https://www.ncbi.nlm.nih.gov/pubmed/30859149
http://dx.doi.org/10.1002/hep4.1305

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