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Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes

During normal proliferation, hepatocytes accumulate triglycerides (TGs) in lipid droplets (LDs), but the underlying mechanisms and functional significance of this steatosis are unknown. In the current study, we examined the coordinated regulation of cell cycle progression and LD accumulation. As pre...

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Detalles Bibliográficos
Autores principales: Wu, Heng, Ploeger, Jonathan M., Kamarajugadda, Sushama, Mashek, Douglas G., Mashek, Mara T., Manivel, Juan C., Shekels, Laurie L., Lapiro, Jessica L., Albrecht, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396375/
https://www.ncbi.nlm.nih.gov/pubmed/30859152
http://dx.doi.org/10.1002/hep4.1316