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Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes
During normal proliferation, hepatocytes accumulate triglycerides (TGs) in lipid droplets (LDs), but the underlying mechanisms and functional significance of this steatosis are unknown. In the current study, we examined the coordinated regulation of cell cycle progression and LD accumulation. As pre...
Autores principales: | Wu, Heng, Ploeger, Jonathan M., Kamarajugadda, Sushama, Mashek, Douglas G., Mashek, Mara T., Manivel, Juan C., Shekels, Laurie L., Lapiro, Jessica L., Albrecht, Jeffrey H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396375/ https://www.ncbi.nlm.nih.gov/pubmed/30859152 http://dx.doi.org/10.1002/hep4.1316 |
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