A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons

[Image: see text] There are few biocatalytic transformations that produce fluorine-containing molecules prevalent in modern pharmaceuticals. To expand the scope of biocatalysis for organofluorine synthesis, we have developed an enzymatic platform for highly enantioselective carbene B–H bond insertio...

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Detalles Bibliográficos
Autores principales: Huang, Xiongyi, Garcia-Borràs, Marc, Miao, Kun, Kan, S. B. Jennifer, Zutshi, Arjun, Houk, K. N., Arnold, Frances H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396380/
https://www.ncbi.nlm.nih.gov/pubmed/30834315
http://dx.doi.org/10.1021/acscentsci.8b00679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396380/
https://www.ncbi.nlm.nih.gov/pubmed/30834315
http://dx.doi.org/10.1021/acscentsci.8b00679

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