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Drug–Membrane Permeability across Chemical Space

[Image: see text] Unraveling the relation between the chemical structure of small druglike compounds and their rate of passive permeation across lipid membranes is of fundamental importance for pharmaceutical applications. The elucidation of a comprehensive structure–permeability relationship expres...

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Detalles Bibliográficos
Autores principales: Menichetti, Roberto, Kanekal, Kiran H., Bereau, Tristan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396385/
https://www.ncbi.nlm.nih.gov/pubmed/30834317
http://dx.doi.org/10.1021/acscentsci.8b00718