Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion

Aneuploidy that arises during meiosis and/or mitosis is a major contributor to early embryo loss. We previously showed that human preimplantation embryos encapsulate missegregated chromosomes into micronuclei while undergoing cellular fragmentation and that fragments can contain chromosomal material...

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Detalles Bibliográficos
Autores principales: Daughtry, Brittany L., Rosenkrantz, Jimi L., Lazar, Nathan H., Fei, Suzanne S., Redmayne, Nash, Torkenczy, Kristof A., Adey, Andrew, Yan, Melissa, Gao, Lina, Park, Byung, Nevonen, Kimberly A., Carbone, Lucia, Chavez, Shawn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396419/
https://www.ncbi.nlm.nih.gov/pubmed/30683754
http://dx.doi.org/10.1101/gr.239830.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396419/
https://www.ncbi.nlm.nih.gov/pubmed/30683754
http://dx.doi.org/10.1101/gr.239830.118

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