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The circular RNome of primary breast cancer

Circular RNAs (circRNAs) are a class of RNAs that is under increasing scrutiny, although their functional roles are debated. We analyzed RNA-seq data of 348 primary breast cancers and developed a method to identify circRNAs that does not rely on unmapped reads or known splice junctions. We identifie...

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Detalles Bibliográficos
Autores principales: Smid, Marcel, Wilting, Saskia M., Uhr, Katharina, Rodríguez-González, F. Germán, de Weerd, Vanja, Prager-Van der Smissen, Wendy J.C., van der Vlugt-Daane, Michelle, van Galen, Anne, Nik-Zainal, Serena, Butler, Adam, Martin, Sancha, Davies, Helen R., Staaf, Johan, van de Vijver, Marc J., Richardson, Andrea L., MacGrogan, Gaëten, Salgado, Roberto, van den Eynden, Gert G.G.M., Purdie, Colin A., Thompson, Alastair M., Caldas, Carlos, Span, Paul N., Sweep, Fred C.G.J., Simpson, Peter T., Lakhani, Sunil R., Van Laere, Steven, Desmedt, Christine, Paradiso, Angelo, Eyfjord, Jorunn, Broeks, Annegien, Vincent-Salomon, Anne, Futreal, Andrew P., Knappskog, Stian, King, Tari, Viari, Alain, Børresen-Dale, Anne-Lise, Stunnenberg, Hendrik G., Stratton, Mike, Foekens, John A., Sieuwerts, Anieta M., Martens, John W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396421/
https://www.ncbi.nlm.nih.gov/pubmed/30692147
http://dx.doi.org/10.1101/gr.238121.118