Amlexanox attenuates experimental autoimmune encephalomyelitis by inhibiting dendritic cell maturation and reprogramming effector and regulatory T cell responses

BACKGROUND: Amlexanox (ALX), a TBK1 inhibitor, can modulate immune responses and has anti-inflammatory properties. To investigate its role in regulating the progression of experimental autoimmune encephalomyelitis (EAE), we studied the effect of ALX on the maturation of dendritic cells (DCs) and the...

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Detalles Bibliográficos
Autores principales: Quan, Mo-Yuan, Song, Xiu-Juan, Liu, Hui-Jia, Deng, Xiao-Hong, Hou, Hui-Qing, Chen, Li-Ping, Ma, Tian-Zhao, Han, Xu, He, Xin-Xin, Jia, Zhen, Guo, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396467/
https://www.ncbi.nlm.nih.gov/pubmed/30823934
http://dx.doi.org/10.1186/s12974-019-1438-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396467/
https://www.ncbi.nlm.nih.gov/pubmed/30823934
http://dx.doi.org/10.1186/s12974-019-1438-z

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