Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein

BACKGROUND: Abnormal aggregation of brain α-synuclein is a central step in the pathogenesis of Parkinson’s disease (PD), thus, it is reliable to promote the clearance of α-synuclein to prevent and treat PD. Recent studies have revealed an essential role of glymphatic system and meningeal lymphatic v...

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Detalles Bibliográficos
Autores principales: Zou, Wenyan, Pu, Tinglin, Feng, Weixi, Lu, Ming, Zheng, Ying, Du, Renhong, Xiao, Ming, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396507/
https://www.ncbi.nlm.nih.gov/pubmed/30867902
http://dx.doi.org/10.1186/s40035-019-0147-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396507/
https://www.ncbi.nlm.nih.gov/pubmed/30867902
http://dx.doi.org/10.1186/s40035-019-0147-y

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