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Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein

BACKGROUND: Abnormal aggregation of brain α-synuclein is a central step in the pathogenesis of Parkinson’s disease (PD), thus, it is reliable to promote the clearance of α-synuclein to prevent and treat PD. Recent studies have revealed an essential role of glymphatic system and meningeal lymphatic v...

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Detalles Bibliográficos
Autores principales:	Zou, Wenyan, Pu, Tinglin, Feng, Weixi, Lu, Ming, Zheng, Ying, Du, Renhong, Xiao, Ming, Hu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396507/ https://www.ncbi.nlm.nih.gov/pubmed/30867902 http://dx.doi.org/10.1186/s40035-019-0147-y

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