Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS

Oncogenic KRAS plays a vital role in controlling tumor metabolism by enhancing aerobic glycolysis. Obesity driven by chronic consumption of high-fat diet (HFD) is a major risk factor for oncogenic KRAS-mediated pancreatic ductal adenocarcinoma (PDAC). However, the role of HFD in KRAS-mediated metabo...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Bi, Yawei, Hu, Lianghao, Luo, Yongde, Ji, Juntao, Mao, Albert Z., Logsdon, Craig D., Li, Ellen, Abbruzzese, James L., Li, Zhaoshen, Yang, Vincent W., Lu, Weiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396546/
https://www.ncbi.nlm.nih.gov/pubmed/30819189
http://dx.doi.org/10.1186/s12964-019-0333-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396546/
https://www.ncbi.nlm.nih.gov/pubmed/30819189
http://dx.doi.org/10.1186/s12964-019-0333-7

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