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Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS

Oncogenic KRAS plays a vital role in controlling tumor metabolism by enhancing aerobic glycolysis. Obesity driven by chronic consumption of high-fat diet (HFD) is a major risk factor for oncogenic KRAS-mediated pancreatic ductal adenocarcinoma (PDAC). However, the role of HFD in KRAS-mediated metabo...

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Detalles Bibliográficos
Autores principales:	Wang, Dan, Bi, Yawei, Hu, Lianghao, Luo, Yongde, Ji, Juntao, Mao, Albert Z., Logsdon, Craig D., Li, Ellen, Abbruzzese, James L., Li, Zhaoshen, Yang, Vincent W., Lu, Weiqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396546/ https://www.ncbi.nlm.nih.gov/pubmed/30819189 http://dx.doi.org/10.1186/s12964-019-0333-7

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