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Comprehensive mitochondrial DNA analysis and IVF outcome

STUDY QUESTION: Do mitochondrial DNA (mtDNA) copy number and heteroplasmy in human embryos affect the ongoing pregnancy rate? SUMMARY ANSWER: Our study suggests that mtDNA copy number above a specific threshold is associated with the ongoing pregnancy rate. WHAT IS KNOWN ALREADY: Mitochondria play a...

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Detalles Bibliográficos
Autores principales: Lledo, B, Ortiz, J A, Morales, R, García-Hernández, E, Ten, J, Bernabeu, A, Llácer, J, Bernabeu, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396640/
https://www.ncbi.nlm.nih.gov/pubmed/30895263
http://dx.doi.org/10.1093/hropen/hoy023