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Multifunctional PLGA-based nanoparticles as a controlled release drug delivery system for antioxidant and anticoagulant therapy
BACKGROUND: Ischemia/reperfusion (I/R) injury causes the generation of many ROS such as H(2)O(2) and leads to vascular thrombosis, which causes tissue damage. PURPOSE: In this investigation, poly (lactideco-glycolide) (PLGA)-based nanoparticles are used for their anticoagulant and antioxidant proper...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396665/ https://www.ncbi.nlm.nih.gov/pubmed/30880963 http://dx.doi.org/10.2147/IJN.S174962 |