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Multifunctional PLGA-based nanoparticles as a controlled release drug delivery system for antioxidant and anticoagulant therapy

BACKGROUND: Ischemia/reperfusion (I/R) injury causes the generation of many ROS such as H(2)O(2) and leads to vascular thrombosis, which causes tissue damage. PURPOSE: In this investigation, poly (lactideco-glycolide) (PLGA)-based nanoparticles are used for their anticoagulant and antioxidant proper...

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Detalles Bibliográficos
Autores principales: Lee, Pei-Chi, Zan, Bo-Shen, Chen, Li-Ting, Chung, Tze-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396665/
https://www.ncbi.nlm.nih.gov/pubmed/30880963
http://dx.doi.org/10.2147/IJN.S174962