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INTS8 accelerates the epithelial-to-mesenchymal transition in hepatocellular carcinoma by upregulating the TGF-β signaling pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is the third leading cause of death by malignancy worldwide. HCC has a poor prognosis due to tumor invasiveness and metastasis. There is substantial evidence that the epithelial-to-mesenchymal transition (EMT) plays a central role in cancer metastasis. In a...

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Detalles Bibliográficos
Autores principales: Tong, Hui, Liu, Xiaohui, Li, Tao, Qiu, Weihua, Peng, Chenghong, Shen, Baiyong, Zhu, Zhecheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396674/
https://www.ncbi.nlm.nih.gov/pubmed/30881114
http://dx.doi.org/10.2147/CMAR.S184392