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A system for production of defective interfering particles in the absence of infectious influenza A virus

Influenza A virus (IAV) infection poses a serious health threat and novel antiviral strategies are needed. Defective interfering particles (DIPs) can be generated in IAV infected cells due to errors of the viral polymerase and may suppress spread of wild type (wt) virus. The antiviral activity of DI...

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Detalles Bibliográficos
Autores principales: Bdeir, Najat, Arora, Prerna, Gärtner, Sabine, Hoffmann, Markus, Reichl, Udo, Pöhlmann, Stefan, Winkler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396908/
https://www.ncbi.nlm.nih.gov/pubmed/30822349
http://dx.doi.org/10.1371/journal.pone.0212757