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A numerical approach for a discrete Markov model for progressing drug resistance of cancer
The presence of treatment-resistant cells is an important factor that limits the efficacy of cancer therapy, and the prospect of resistance is considered the major cause of the treatment strategy. Several recent studies have employed mathematical models to elucidate the dynamics of generating resist...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396936/ https://www.ncbi.nlm.nih.gov/pubmed/30779730 http://dx.doi.org/10.1371/journal.pcbi.1006770 |