Human IFIT proteins inhibit lytic replication of KSHV: A new feed-forward loop in the innate immune system

Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally associated with Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The IFIT family of proteins inhibits replication of some viruses, but their effects on KSHV lytic replication was unknown. Here we show t...

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Detalles Bibliográficos
Autores principales: Li, Dajiang, Swaminathan, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396945/
https://www.ncbi.nlm.nih.gov/pubmed/30779786
http://dx.doi.org/10.1371/journal.ppat.1007609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396945/
https://www.ncbi.nlm.nih.gov/pubmed/30779786
http://dx.doi.org/10.1371/journal.ppat.1007609

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