Identifying individual risk rare variants using protein structure guided local tests (POINT)

Rare variants are of increasing interest to genetic association studies because of their etiological contributions to human complex diseases. Due to the rarity of the mutant events, rare variants are routinely analyzed on an aggregate level. While aggregation analyses improve the detection of global...

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Detalles Bibliográficos
Autores principales: Marceau West, Rachel, Lu, Wenbin, Rotroff, Daniel M., Kuenemann, Melaine A., Chang, Sheng-Mao, Wu, Michael C., Wagner, Michael J., Buse, John B., Motsinger-Reif, Alison A., Fourches, Denis, Tzeng, Jung-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396946/
https://www.ncbi.nlm.nih.gov/pubmed/30779729
http://dx.doi.org/10.1371/journal.pcbi.1006722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396946/
https://www.ncbi.nlm.nih.gov/pubmed/30779729
http://dx.doi.org/10.1371/journal.pcbi.1006722

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