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Functional lability of RNA-dependent RNA polymerases in animals

RNA interference (RNAi) requires RNA-dependent RNA polymerases (RdRPs) in many eukaryotes, and RNAi amplification constitutes the only known function for eukaryotic RdRPs. Yet in animals, classical model organisms can elicit RNAi without possessing RdRPs, and only nematode RNAi was shown to require...

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Detalles Bibliográficos
Autores principales: Pinzón, Natalia, Bertrand, Stéphanie, Subirana, Lucie, Busseau, Isabelle, Escrivá, Hector, Seitz, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396948/
https://www.ncbi.nlm.nih.gov/pubmed/30779744
http://dx.doi.org/10.1371/journal.pgen.1007915