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Multi-modality in gene regulatory networks with slow promoter kinetics
Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with alternative states of complex nonlinear systems: stable attractors in determinis...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396950/ https://www.ncbi.nlm.nih.gov/pubmed/30779734 http://dx.doi.org/10.1371/journal.pcbi.1006784 |