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Multi-modality in gene regulatory networks with slow promoter kinetics

Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with alternative states of complex nonlinear systems: stable attractors in determinis...

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Detalles Bibliográficos
Autores principales: Ali Al-Radhawi, M., Del Vecchio, Domitilla, Sontag, Eduardo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396950/
https://www.ncbi.nlm.nih.gov/pubmed/30779734
http://dx.doi.org/10.1371/journal.pcbi.1006784