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Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)

OBJECTIVE: To identify novel genetic associations with white matter hyperintensities (WMH). METHODS: We performed a genome-wide association meta-analysis of WMH volumes in 11,226 individuals, including 8,429 population-based individuals from UK Biobank and 2,797 stroke patients. Replication of novel...

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Detalles Bibliográficos
Autores principales: Traylor, Matthew, Tozer, Daniel J., Croall, Iain D., Lisiecka Ford, Danuta M., Olorunda, Abiodun Olubunmi, Boncoraglio, Giorgio, Dichgans, Martin, Lemmens, Robin, Rosand, Jonathan, Rost, Natalia S., Rothwell, Peter M., Sudlow, Cathie L.M., Thijs, Vincent, Rutten-Jacobs, Loes, Markus, Hugh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396967/
https://www.ncbi.nlm.nih.gov/pubmed/30659137
http://dx.doi.org/10.1212/WNL.0000000000006952