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The Atypical MAP Kinase ErkB Transmits Distinct Chemotactic Signals through a Core Signaling Module

Signaling from chemoattractant receptors activates the cytoskeleton of crawling cells for chemotaxis. We show using phosphoproteomics that different chemoattractants cause phosphorylation of the same core set of around 80 proteins in Dictyostelium cells. Strikingly, the majority of these are phospho...

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Detalles Bibliográficos
Autores principales: Nichols, John M.E., Paschke, Peggy, Peak-Chew, Sew, Williams, Thomas D., Tweedy, Luke, Skehel, Mark, Stephens, Elaine, Chubb, Jonathan R., Kay, Robert R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397043/
https://www.ncbi.nlm.nih.gov/pubmed/30612939
http://dx.doi.org/10.1016/j.devcel.2018.12.001