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The Essentiality Status of Mouse Duplicate Gene Pairs Correlates with Developmental Co-Expression Patterns

During the evolution of multicellular eukaryotes, gene duplication occurs frequently to generate new genes and/or functions. A duplicated gene may have a similar function to its ancestral gene. Therefore, it may be expected that duplicated genes are less likely to be critical for the survival of an...

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Detalles Bibliográficos
Autores principales: Kabir, Mitra, Wenlock, Stephanie, Doig, Andrew J., Hentges, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397145/
https://www.ncbi.nlm.nih.gov/pubmed/30824779
http://dx.doi.org/10.1038/s41598-019-39894-9