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A Novel Hybrid Cytokine IL233 Mediates regeneration following Doxorubicin-Induced Nephrotoxic Injury

Kidney injury, whether due to ischemic insults or chemotherapeutic agents, is exacerbated by inflammation, whereas Tregs are protective. We recently showed that IL-2 and IL-33, especially as a hybrid cytokine (IL233 - bearing IL-2 and IL-33 activities in one molecule), potentiated Tregs and group 2...

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Detalles Bibliográficos
Autores principales: Sabapathy, Vikram, Cheru, Nardos Tesfaye, Corey, Rebecca, Mohammad, Saleh, Sharma, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397151/
https://www.ncbi.nlm.nih.gov/pubmed/30824764
http://dx.doi.org/10.1038/s41598-019-39886-9