Activation of the PERK-ATF4 pathway promotes chemo-resistance in colon cancer cells

Colon cancer is a major health problem worldwide. While chemotherapy remains a main approach for treating late-stage colon cancer patients, most, if not all, of them will develop drug resistance and die of uncontrollable disease progression eventually. Therefore, identification of mechanism of drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Zhong, Yu, Xiaofu, Yuan, Meiqin, Lv, Wangxia, Feng, Tingting, Bai, Rui, Zhong, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397152/
https://www.ncbi.nlm.nih.gov/pubmed/30824833
http://dx.doi.org/10.1038/s41598-019-39547-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397152/
https://www.ncbi.nlm.nih.gov/pubmed/30824833
http://dx.doi.org/10.1038/s41598-019-39547-x

Ejemplares similares