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Activation of the PERK-ATF4 pathway promotes chemo-resistance in colon cancer cells

Colon cancer is a major health problem worldwide. While chemotherapy remains a main approach for treating late-stage colon cancer patients, most, if not all, of them will develop drug resistance and die of uncontrollable disease progression eventually. Therefore, identification of mechanism of drug...

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Detalles Bibliográficos
Autores principales:	Shi, Zhong, Yu, Xiaofu, Yuan, Meiqin, Lv, Wangxia, Feng, Tingting, Bai, Rui, Zhong, Haijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397152/ https://www.ncbi.nlm.nih.gov/pubmed/30824833 http://dx.doi.org/10.1038/s41598-019-39547-x

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