Cargando…

Src in endosomal membranes promotes exosome secretion and tumor progression

c-Src is a membrane-associated tyrosine kinase that has key roles in the signaling transduction that controls cell growth, adhesion, and migration. In the early stage of carcinogenesis, c-Src is activated under the plasma membrane and transduces oncogenic signals. Here we show that c-Src localized t...

Descripción completa

Detalles Bibliográficos
Autores principales: Hikita, Tomoya, Kuwahara, Atsushi, Watanabe, Risayo, Miyata, Mamiko, Oneyama, Chitose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397170/
https://www.ncbi.nlm.nih.gov/pubmed/30824759
http://dx.doi.org/10.1038/s41598-019-39882-z