Prioritizing Parkinson’s disease genes using population-scale transcriptomic data

Genome-wide association studies (GWAS) have identified over 41 susceptibility loci associated with Parkinson’s Disease (PD) but identifying putative causal genes and the underlying mechanisms remains challenging. Here, we leverage large-scale transcriptomic datasets to prioritize genes that are like...

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Detalles Bibliográficos
Autores principales: Li, Yang I., Wong, Garrett, Humphrey, Jack, Raj, Towfique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397174/
https://www.ncbi.nlm.nih.gov/pubmed/30824768
http://dx.doi.org/10.1038/s41467-019-08912-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397174/
https://www.ncbi.nlm.nih.gov/pubmed/30824768
http://dx.doi.org/10.1038/s41467-019-08912-9

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