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Prioritizing Parkinson’s disease genes using population-scale transcriptomic data
Genome-wide association studies (GWAS) have identified over 41 susceptibility loci associated with Parkinson’s Disease (PD) but identifying putative causal genes and the underlying mechanisms remains challenging. Here, we leverage large-scale transcriptomic datasets to prioritize genes that are like...
Autores principales: | Li, Yang I., Wong, Garrett, Humphrey, Jack, Raj, Towfique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397174/ https://www.ncbi.nlm.nih.gov/pubmed/30824768 http://dx.doi.org/10.1038/s41467-019-08912-9 |
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