Cargando…

Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

Excitotoxicity, caused by overstimulation or dysregulation of ionotropic glutamate receptors (iGluRs), is a pathological process directing neuronal death in many neurological disorders. The aberrantly stimulated iGluRs direct massive influx of calcium ions into the affected neurons, leading to chang...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoque, Ashfaqul, Williamson, Nicholas A., Ameen, S. Sadia, Ciccotosto, Giuseppe D., Hossain, M. Iqbal, Oakhill, Jonathan S., Ng, Dominic C. H., Ang, Ching-Seng, Cheng, Heung-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397184/
https://www.ncbi.nlm.nih.gov/pubmed/30824683
http://dx.doi.org/10.1038/s41419-019-1445-0