PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy

Personalized cancer therapy relies on identifying patient subsets that benefit from a therapeutic intervention and suggest alternative regimens for those who don’t. A new data integrative approach, based on graphical models, was applied on our multi-modal –omics, and clinical data cohort of metastat...

Descripción completa

Detalles Bibliográficos
Autores principales: Abecassis, Irina, Sedgewick, Andrew J., Romkes, Marjorie, Buch, Shama, Nukui, Tomoko, Kapetanaki, Maria G., Vogt, Andreas, Kirkwood, John M., Benos, Panayiotis V., Tawbi, Hussein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397203/
https://www.ncbi.nlm.nih.gov/pubmed/30824778
http://dx.doi.org/10.1038/s41598-019-39542-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397203/
https://www.ncbi.nlm.nih.gov/pubmed/30824778
http://dx.doi.org/10.1038/s41598-019-39542-2

Ejemplares similares