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Toll-Like Receptor 4 Activation Promotes Multiple Myeloma Cell Growth and Survival Via Suppression of The Endoplasmic Reticulum Stress Factor Chop

Despite recent biomedical improvements in treating Multiple Myeloma (MM), the disease still remains incurable. Toll like receptors (TLRs) provide a link between innate and adaptive immune responses and hence potentially correlate inflammation to cancer. Although the regulatory role of TLRs in MM has...

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Detalles Bibliográficos
Autores principales: Bagratuni, Tina, Sklirou, Aimilia D., Kastritis, Efstathios, Liacos, Christine Ivy, Spilioti, Christina, Eleutherakis-Papaiakovou, Evangelos, Kanellias, Nikolaos, Gavriatopoulou, Maria, Terpos, Evangelos, Trougakos, Ioannis P., Dimopoulos, Meletios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397208/
https://www.ncbi.nlm.nih.gov/pubmed/30824741
http://dx.doi.org/10.1038/s41598-019-39672-7