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A micropatterning platform for quantifying interaction kinetics between the T cell receptor and an intracellular binding protein

A complete understanding of signaling processes at the plasma membrane depends on a quantitative characterization of the interactions of the involved proteins. Fluorescence recovery after photobleaching (FRAP) is a widely used and convenient technique to obtain kinetic parameters on protein interact...

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Detalles Bibliográficos
Autores principales: Motsch, Viktoria, Brameshuber, Mario, Baumgart, Florian, Schütz, Gerhard J., Sevcsik, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397226/
https://www.ncbi.nlm.nih.gov/pubmed/30824760
http://dx.doi.org/10.1038/s41598-019-39865-0