Rapid analysis of intraperitoneally administered morphine in mouse plasma and brain by microchip electrophoresis-electrochemical detection

Animal studies remain an essential part of drug discovery since in vitro models are not capable of describing the complete living organism. We developed and qualified a microchip electrophoresis-electrochemical detection (MCE-EC) method for rapid analysis of morphine in mouse plasma using a commerci...

Descripción completa

Detalles Bibliográficos
Autores principales: Ollikainen, Elisa, Aitta-aho, Teemu, Koburg, Michaela, Kostiainen, Risto, Sikanen, Tiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397260/
https://www.ncbi.nlm.nih.gov/pubmed/30824794
http://dx.doi.org/10.1038/s41598-019-40116-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397260/
https://www.ncbi.nlm.nih.gov/pubmed/30824794
http://dx.doi.org/10.1038/s41598-019-40116-5

Ejemplares similares