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Rapid analysis of intraperitoneally administered morphine in mouse plasma and brain by microchip electrophoresis-electrochemical detection
Animal studies remain an essential part of drug discovery since in vitro models are not capable of describing the complete living organism. We developed and qualified a microchip electrophoresis-electrochemical detection (MCE-EC) method for rapid analysis of morphine in mouse plasma using a commerci...
Autores principales: | Ollikainen, Elisa, Aitta-aho, Teemu, Koburg, Michaela, Kostiainen, Risto, Sikanen, Tiina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397260/ https://www.ncbi.nlm.nih.gov/pubmed/30824794 http://dx.doi.org/10.1038/s41598-019-40116-5 |
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