Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin

In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide (CPP) with high translocation activity, was conjugated with vancomycin (Van), which is known for poor access to the intracellular bacteria and the brain. The antibacterial activity of the conjugates was tested on...

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Detalles Bibliográficos
Autores principales: Ruczyński, Jarosław, Rusiecka, Izabela, Turecka, Katarzyna, Kozłowska, Agnieszka, Alenowicz, Magdalena, Gągało, Iwona, Kawiak, Anna, Rekowski, Piotr, Waleron, Krzysztof, Kocić, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397271/
https://www.ncbi.nlm.nih.gov/pubmed/30824786
http://dx.doi.org/10.1038/s41598-019-40103-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397271/
https://www.ncbi.nlm.nih.gov/pubmed/30824786
http://dx.doi.org/10.1038/s41598-019-40103-w

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