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Differential metabolic activity and discovery of therapeutic targets using summarized metabolic pathway models

In spite of the increasing availability of genomic and transcriptomic data, there is still a gap between the detection of perturbations in gene expression and the understanding of their contribution to the molecular mechanisms that ultimately account for the phenotype studied. Alterations in the met...

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Detalles Bibliográficos
Autores principales: Çubuk, Cankut, Hidalgo, Marta R., Amadoz, Alicia, Rian, Kinza, Salavert, Francisco, Pujana, Miguel A., Mateo, Francesca, Herranz, Carmen, Carbonell-Caballero, Jose, Dopazo, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397295/
https://www.ncbi.nlm.nih.gov/pubmed/30854222
http://dx.doi.org/10.1038/s41540-019-0087-2