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Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders
The hypothalamic-pituitary-adrenal (HPA) axis regulates responses to internal and external stressors. Many patients diagnosed with conditions such as depression or anxiety also have hyperactivity of the HPA axis. Hyper-stimulation of the HPA axis results in sustained elevated levels of glucocorticoi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397323/ https://www.ncbi.nlm.nih.gov/pubmed/30824750 http://dx.doi.org/10.1038/s41598-019-39867-y |