Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders

The hypothalamic-pituitary-adrenal (HPA) axis regulates responses to internal and external stressors. Many patients diagnosed with conditions such as depression or anxiety also have hyperactivity of the HPA axis. Hyper-stimulation of the HPA axis results in sustained elevated levels of glucocorticoi...

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Detalles Bibliográficos
Autores principales: Gannon, Anne-Louise, O’Hara, Laura, Mason, J. Ian, Rebourcet, Diane, Smith, Sarah, Traveres, Adriana, Alcaide-Corral, Carlos Jose, Frederiksen, Hanne, Jørgensen, Anne, Milne, Laura, Mitchell, Rod T., Smith, Lee B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397323/
https://www.ncbi.nlm.nih.gov/pubmed/30824750
http://dx.doi.org/10.1038/s41598-019-39867-y

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