Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome

Hypoxic pulmonary vasoconstriction (HPV) is a physiological vasomotor response that maintains systemic oxygenation by matching perfusion to ventilation during alveolar hypoxia. Although mitochondria appear to play an essential role in HPV, the impact of mitochondrial dysfunction on HPV remains incom...

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Detalles Bibliográficos
Autores principales: Schleifer, Grigorij, Marutani, Eizo, Ferrari, Michele, Sharma, Rohit, Skinner, Owen, Goldberger, Olga, Grange, Robert Matthew Henry, Peneyra, Kathryn, Malhotra, Rajeev, Wepler, Martin, Ichinose, Fumito, Bloch, Donald B., Mootha, Vamsi K., Zapol, Warren M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397345/
https://www.ncbi.nlm.nih.gov/pubmed/30520688
http://dx.doi.org/10.1152/ajplung.00419.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397345/
https://www.ncbi.nlm.nih.gov/pubmed/30520688
http://dx.doi.org/10.1152/ajplung.00419.2018

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