Cargando…

Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome

Hypoxic pulmonary vasoconstriction (HPV) is a physiological vasomotor response that maintains systemic oxygenation by matching perfusion to ventilation during alveolar hypoxia. Although mitochondria appear to play an essential role in HPV, the impact of mitochondrial dysfunction on HPV remains incom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schleifer, Grigorij, Marutani, Eizo, Ferrari, Michele, Sharma, Rohit, Skinner, Owen, Goldberger, Olga, Grange, Robert Matthew Henry, Peneyra, Kathryn, Malhotra, Rajeev, Wepler, Martin, Ichinose, Fumito, Bloch, Donald B., Mootha, Vamsi K., Zapol, Warren M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Physiological Society 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397345/ https://www.ncbi.nlm.nih.gov/pubmed/30520688 http://dx.doi.org/10.1152/ajplung.00419.2018

Ejemplares similares

Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia
por: Petersen, Bodil, et al.
Publicado: (2019)

An engineered enzyme that targets circulating lactate to alleviate intracellular NADH/NAD(+) imbalance
por: Patgiri, Anupam, et al.
Publicado: (2020)

Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreich’s ataxia
por: Ast, Tslil, et al.
Publicado: (2023)

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome
por: Ferrari, Michele, et al.
Publicado: (2017)

Emerging pharmacological tools to control hydrogen sulfide signaling in critical illness
por: Marutani, Eizo, et al.
Publicado: (2020)

Mitochondrial dysfunction remodels one-carbon metabolism in human cells
por: Bao, Xiaoyan Robert, et al.
Publicado: (2016)

On the dynamic and even reversible nature of Leigh syndrome: Lessons from human imaging and mouse models
por: Walker, Melissa A., et al.
Publicado: (2022)

Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia
por: Kanemaru, Eiki, et al.
Publicado: (2023)

Hypoxic Pulmonary Vasoconstriction in Humans
por: Ariyaratnam, Priyadharshanan, et al.
Publicado: (2013)

Trapping Hydrogen Sulfide (H(2)S) with Diselenides: The Application in the Design of Fluorescent Probes
por: Peng, Bo, et al.
Publicado: (2015)

Hypoxic Pulmonary Vasoconstriction in Humans: Tale or Myth
por: Hussain, A., et al.
Publicado: (2017)

Mitochondrial transplantation attenuates hypoxic pulmonary vasoconstriction
por: Zhou, Juan, et al.
Publicado: (2016)

Adult-onset Leigh Syndrome with a m.9176T>C Mutation Manifested As Reversible Cerebral Vasoconstriction Syndrome
por: Ohyama-Tamagake, Ayane, et al.
Publicado: (2022)

Inhibition of Hypoxic Pulmonary Vasoconstriction of Rats by Carbon Monoxide
por: Yoo, Hae Young, et al.
Publicado: (2010)

Sulfide catabolism ameliorates hypoxic brain injury
por: Marutani, Eizo, et al.
Publicado: (2021)

A Metabolic Signature of Mitochondrial Dysfunction Revealed through a Monogenic Form of Leigh Syndrome
por: Thompson Legault, Julie, et al.
Publicado: (2015)

Reversible Vasoconstriction Syndrome Is a Complication of SARS-CoV-2 Infection/Vaccination Rather than That of Leigh Syndrome
por: Finsterer, Josef, et al.
Publicado: (2023)

Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction
por: Cogolludo, Angel, et al.
Publicado: (2009)

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction
por: Ketabchi, Farzaneh, et al.
Publicado: (2012)

Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels
por: Sweeney, Michèle, et al.
Publicado: (2000)

Impairment of hypoxic pulmonary vasoconstriction in acute respiratory distress syndrome
por: Gierhardt, Mareike, et al.
Publicado: (2021)

Dual role of the L-arginine–ADMA–NO pathway in systemic hypoxic vasodilation and pulmonary hypoxic vasoconstriction
por: Böger, Rainer, et al.
Publicado: (2020)

Revisiting the mechanism of hypoxic pulmonary vasoconstriction using isolated perfused/ventilated mouse lung
por: Jain, Pritesh P., et al.
Publicado: (2020)

Sulfide:quinone oxidoreductase ameliorates neurodegeneration in a murine model of Parkinson's disease
por: Nagashima, Fumiaki, et al.
Publicado: (2022)

Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery
por: Knock, Greg A., et al.
Publicado: (2008)

Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs
por: Hubloue, Ives, et al.
Publicado: (2004)

Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6
por: Fuchs, Beate, et al.
Publicado: (2011)

Riociguat versus sildenafil on hypoxic pulmonary vasoconstriction and ventilation/perfusion matching
por: Chamorro, Virginia, et al.
Publicado: (2018)

Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
por: Turzo, Maurizio, et al.
Publicado: (2018)

Inhibition of ornithine decarboxylase restores hypoxic pulmonary vasoconstriction in endotoxemic mice
por: Gebauer, P.H., et al.
Publicado: (2020)

The hypoxic pulmonary vasoconstriction: From physiology to clinical application in thoracic surgery
por: Licker, Marc, et al.
Publicado: (2021)

Imaging Depiction of Hypoxic Pulmonary Vasoconstriction Using Dual-Energy CT
por: Hunter, Joshua G, et al.
Publicado: (2023)

Reply to the Letter “Reversible Vasoconstriction Syndrome Is a Complication of SARS-CoV-2 Infection/Vaccination Rather than That of Leigh Syndrome”
por: Ohyama-Tamagake, Ayane, et al.
Publicado: (2023)

UBA6 and NDFIP1 regulate the degradation of ferroportin
por: Traeger, Lisa, et al.
Publicado: (2021)

Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics
por: Flicker, Daniel, et al.
Publicado: (2019)

Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction
por: Egemnazarov, Bakytbek, et al.
Publicado: (2010)

Optimization of isolated perfused/ventilated mouse lung to study hypoxic pulmonary vasoconstriction
por: Yoo, Hae Young, et al.
Publicado: (2013)

Human hypoxic pulmonary vasoconstriction is unaltered by 8 h of preceding isocapnic hyperoxia
por: Cheng, Hung‐Yuan, et al.
Publicado: (2017)

Oral Administration of Glutathione Trisulfide Increases Reactive Sulfur Levels in Dorsal Root Ganglion and Ameliorates Paclitaxel-Induced Peripheral Neuropathy in Mice
por: Ezaka, Mariko, et al.
Publicado: (2022)

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells
por: Nakagawa, Akito, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jn58vr4b1t19hac4rcsl9spcl7