Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development

BACKGROUND: Cancer cells are characterized by chromosomal instability (CIN) and it is thought that errors in pathways involved in faithful chromosome segregation play a pivotal role in the genesis of CIN. Cohesin forms a large protein ring that binds DNA strands by encircling them. In addition to th...

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Detalles Bibliográficos
Autores principales: Sarogni, Patrizia, Palumbo, Orazio, Servadio, Adele, Astigiano, Simonetta, D’Alessio, Barbara, Gatti, Veronica, Cukrov, Dubravka, Baldari, Silvia, Pallotta, Maria Michela, Aretini, Paolo, Dell’Orletta, Felice, Soddu, Silvia, Carella, Massimo, Toietta, Gabriele, Barbieri, Ottavia, Fontanini, Gabriella, Musio, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397456/
https://www.ncbi.nlm.nih.gov/pubmed/30823889
http://dx.doi.org/10.1186/s13046-019-1116-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397456/
https://www.ncbi.nlm.nih.gov/pubmed/30823889
http://dx.doi.org/10.1186/s13046-019-1116-0

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