A frame-shifted gene, which rescued its function by non-natural start codons and its application in constructing synthetic gene circuits

BACKGROUND: Frame-shifted genes results in non-functional peptides. Because of this complete loss of function, frame-shifted genes have never been used in constructing synthetic gene circuits. RESULTS: Here we report that the function of gene circuits is rescued by a frame-shifted gene, which functi...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarkar, Kathakali, Mukhopadhyay, Sayak, Bonnerjee, Deepro, Srivastava, Rajkamal, Bagh, Sangram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397469/
https://www.ncbi.nlm.nih.gov/pubmed/30867677
http://dx.doi.org/10.1186/s13036-019-0151-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397469/
https://www.ncbi.nlm.nih.gov/pubmed/30867677
http://dx.doi.org/10.1186/s13036-019-0151-x

Ejemplares similares