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A frame-shifted gene, which rescued its function by non-natural start codons and its application in constructing synthetic gene circuits
BACKGROUND: Frame-shifted genes results in non-functional peptides. Because of this complete loss of function, frame-shifted genes have never been used in constructing synthetic gene circuits. RESULTS: Here we report that the function of gene circuits is rescued by a frame-shifted gene, which functi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397469/ https://www.ncbi.nlm.nih.gov/pubmed/30867677 http://dx.doi.org/10.1186/s13036-019-0151-x |