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Nuclear lncRNA HOXD-AS1 suppresses colorectal carcinoma growth and metastasis via inhibiting HOXD3-induced integrin β3 transcriptional activating and MAPK/AKT signalling

BACKGROUND: Long noncoding RNAs (lncRNAs) have been indicated to play critical roles in cancer development and progression. LncRNA HOXD cluster antisense RNA1 (HOXD-AS1) has recently been found to be dysregulated in several cancers. However, the expression levels, cellular localization, precise func...

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Detalles Bibliográficos
Autores principales: Yang, Min-Hui, Zhao, Li, Wang, Lan, Ou-Yang, Wen, Hu, Sha-Sha, Li, Wen-Lu, Ai, Mei-Ling, Wang, Yi-Qing, Han, Yue, Li, Ting-Ting, Ding, Yan-Qing, Wang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397497/
https://www.ncbi.nlm.nih.gov/pubmed/30823921
http://dx.doi.org/10.1186/s12943-019-0955-9