M-Ras/Shoc2 signaling modulates E-cadherin turnover and cell–cell adhesion during collective cell migration

Collective cell migration is required for normal embryonic development and contributes to various biological processes, including wound healing and cancer cell invasion. The M-Ras GTPase and its effector, the Shoc2 scaffold, are proteins mutated in the developmental RASopathy Noonan syndrome, and, h...

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Detalles Bibliográficos
Autores principales: Kota, Pradeep, Terrell, Elizabeth M., Ritt, Daniel A., Insinna, Christine, Westlake, Christopher J., Morrison, Deborah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397545/
https://www.ncbi.nlm.nih.gov/pubmed/30808747
http://dx.doi.org/10.1073/pnas.1805919116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397545/
https://www.ncbi.nlm.nih.gov/pubmed/30808747
http://dx.doi.org/10.1073/pnas.1805919116

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