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Cold sensing by Na(V)1.8-positive and Na(V)1.8-negative sensory neurons

The ability to detect environmental cold serves as an important survival tool. The sodium channels Na(V)1.8 and Na(V)1.9, as well as the TRP channel Trpm8, have been shown to contribute to cold sensation in mice. Surprisingly, transcriptional profiling shows that Na(V)1.8/Na(V)1.9 and Trpm8 are expr...

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Detalles Bibliográficos
Autores principales: Luiz, A. P., MacDonald, D. I., Santana-Varela, S., Millet, Q., Sikandar, S., Wood, J. N., Emery, E. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397562/
https://www.ncbi.nlm.nih.gov/pubmed/30755524
http://dx.doi.org/10.1073/pnas.1814545116