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Cold sensing by Na(V)1.8-positive and Na(V)1.8-negative sensory neurons
The ability to detect environmental cold serves as an important survival tool. The sodium channels Na(V)1.8 and Na(V)1.9, as well as the TRP channel Trpm8, have been shown to contribute to cold sensation in mice. Surprisingly, transcriptional profiling shows that Na(V)1.8/Na(V)1.9 and Trpm8 are expr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397562/ https://www.ncbi.nlm.nih.gov/pubmed/30755524 http://dx.doi.org/10.1073/pnas.1814545116 |