Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

Antimicrobial peptides, in particular α-defensins expressed by Paneth cells, control microbiota composition and play a key role in intestinal barrier function and homeostasis. Dynamic conditions in the local microenvironment, such as pH and redox potential, significantly affect the antimicrobial spe...

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Detalles Bibliográficos
Autores principales: Ehmann, D., Wendler, J., Koeninger, L., Larsen, I. S., Klag, T., Berger, J., Marette, A., Schaller, M., Stange, E. F., Malek, N. P., Jensen, B. A. H., Wehkamp, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397583/
https://www.ncbi.nlm.nih.gov/pubmed/30808760
http://dx.doi.org/10.1073/pnas.1817376116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397583/
https://www.ncbi.nlm.nih.gov/pubmed/30808760
http://dx.doi.org/10.1073/pnas.1817376116

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