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HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission
Human cytomegalovirus (HCMV) causes substantial disease in transplant patients and harms the development of the nervous system in babies infected in utero. Thus, there is a major focus on developing safe and effective HCMV vaccines. Evidence has been presented that a major target of neutralizing ant...
Autores principales: | Vanarsdall, Adam L., Chin, Andrea L., Liu, Jing, Jardetzky, Theodore S., Mudd, James O., Orloff, Susan L., Streblow, Daniel, Mussi-Pinhata, Marisa M., Yamamoto, Aparecida Y., Duarte, Geraldo, Britt, William J., Johnson, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397592/ https://www.ncbi.nlm.nih.gov/pubmed/30733288 http://dx.doi.org/10.1073/pnas.1814835116 |
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